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toned    音标拼音: [t'ond]
a. 具有某种音质的

具有某种音质的

toned
adj 1: having or characterized or distinguished by tone or a
specific tone; often used in combination; "full-toned";
"shrill-toned"; "deep-toned"
2: having or distinguished by a tone; often used in combination;
"full-toned"; "silver-toned" [ant: {toneless}]

Tone \Tone\, v. t. [imp. & p. p. {Toned}; p. pr. & vb. n.
{Toning}.]
1. To utter with an affected tone.
[1913 Webster]

2. To give tone, or a particular tone, to; to tune. See
{Tune}, v. t.
[1913 Webster]

3. (Photog.) To bring, as a print, to a certain required
shade of color, as by chemical treatment.
[1913 Webster]

{To tone down}.
(a) To cause to give lower tone or sound; to give a lower
tone to.
(b) (Paint.) To modify, as color, by making it less
brilliant or less crude; to modify, as a composition
of color, by making it more harmonius.
[1913 Webster]

Its thousand hues toned down harmoniusly. --C.
Kingsley.
[1913 Webster]
(c) Fig.: To moderate or relax; to diminish or weaken the
striking characteristics of; to soften.
[1913 Webster]

The best method for the purpose in hand was to
employ some one of a character and position
suited to get possession of their confidence,
and then use it to tone down their religious
strictures. --Palfrey.
[1913 Webster]

{To tone up}, to cause to give a higher tone or sound; to
give a higher tone to; to make more intense; to heighten;
to strengthen.
[1913 Webster]


Toned \Toned\, a.
Having (such) a tone; -- chiefly used in composition; as,
high-toned; sweet-toned.
[1913 Webster]

{Toned paper}, paper having a slight tint, in distinction
from paper which is quite white.
[1913 Webster]


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英文字典中文字典相关资料:


  • Structural basis of gene regulation by the tetracycline inducible Tet . . .
    The tetracycline repressor (TetR) regulates the most abundant resistance mechanism against the antibiotic tetracycline in gram-negative bacteria
  • Tet Repressor Induction by Tetracycline: A Molecular Dynamics . . .
    In the absence of Tc, TetR is tightly bound to its operator DNA; upon binding of Tc with an associated Mg 2+ ion, it dissociates from the DNA, allowing expression of the repressed genes Its tight control by Tc makes TetR broadly useful in genetic engineering
  • Structure of the Tet Repressor-tetracycline Complex and . . . - AAAS
    The most frequently occurring resistance of Gram-negative bacteria against tetracyclines is triggered by drug recognition of the Tet repressor This causes dissociation of the repressor-operator DNA complex and enables expression of the resistance protein TetA, which is responsible for active efflux of tetracycline
  • Interaction of Tet repressor with operator DNA and with tetracycline . . .
    Interaction of Tet repressor with operator DNA and with tetracycline studied by infrared and Raman spectroscopy Tet repressor (TetR) is involved in the most abundant mechanism of tetracycline (Tc) resistance of gram-negative bacteria
  • TetR - Wikipedia
    There is a binding cavity for tetracycline in the outer helices of the regulatory domain When tetracycline binds this cavity, it causes a conformational change that affects the DNA-binding domain so that TetR is no longer able to bind DNA As a result, TetA and TetR are expressed
  • Tetracycline-controlled transcriptional activation - Wikipedia
    In a Tet-Off system, expression of TRE-controlled genes can be repressed by tetracycline and its derivatives They bind tTA and render it incapable of binding to TRE sequences, thereby preventing transactivation of TRE-controlled genes A Tet-On system works similarly, but in the opposite fashion
  • Tetracycline (Tet) Inducible Expression - Addgene
    In 1995, Gossen et al demonstrated that mutating the amino acid residues of TetR that were important for tetracycline-dependent repression led to a reverse Tet repressor, or rTetR, which specifically binds the TRE in the presence of tetracycline
  • Contacts between Tet repressor and tet operator revealed by new . . .
    We have analyzed the DNA binding properties of Tet-repressor mutants with single amino acid residue replacements at eight positions within the α-helix-turn-α-helix DNA-binding motif
  • Tet repressor binding induced curvature of tet operator DNA
    Tet repressor dimer binds to two tet operator sites spaced by 30 bp in the Tn10 encoded tet regulatory DNA The effect of repressor binding on the gel mobility of circular permutated DNA fragments containing either one or both operator sequences is reported
  • Gene regulation by the tetracycline-inducible Tet repressor-operator . . .
    At present, three-dimensional structures characterizing specific tetracycline protein interactions are available only for the Tet repressor, TetR This is the regulatory switch for the most common resistance mechanism against tetracyclines, Tc, in Gram-negative bacteria





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