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  • What is amyloidosis and 10 signs you might have it
    Amyloidosis (am-uh-loi-DO-sis) is a rare disease that occurs when a substance called amyloid builds up in your organs Amyloid is an abnormal protein that is produced in your bone marrow and can be deposited in any tissue or organ Amyloidosis frequently affects the heart, kidneys, liver, spleen, nervous system and digestive tract It is often […]
  • Cardiac amyloidosis 101: Why early diagnosis and targeted treatment . . .
    When it occurs in the heart, it's called cardiac amyloidosis Dr Martha Grogan, a Mayo Clinic cardiologist and director of the Cardiac Amyloid Clinic at Mayo Clinic in Rochester, Minnesota, explains what cardiac amyloidosis is, why knowing the type of amyloid is key to treatment, and what's on the horizon to help patients with this rare condition
  • Mayo Clinic Q A podcast: Successful treatment of cardiac amyloidosis . . .
    Cardiac amyloidosis typically presents as a form of congestive heart failure It is often overlooked because the symptoms can masquerade as other conditions Unfortunately, there aren't any preventive strategies for cardiac amyloidosis, says Dr Melissa Lyle, a Mayo Clinic cardiologist "So the key, really, is early detection," says Dr Lyle
  • Mayo Clinic Researchers Find Way to Prevent Accumulation of Amyloid . . .
    JACKSONVILLE, Fla — Mayo Clinic researchers led a laboratory study that found a new way to prevent the accumulation of amyloid plaque – a key feature of Alzheimer’s disease – by eliminating a class of molecules called heparan sulfates that form on brain cells “Just as a carpet covers a floor and can hold dirt, molecules […]
  • Spotlight on early detection of 3 heart diseases using ECG-AI
    Mayo Clinic has developed ECG-AI algorithms that are currently used in research to predict a patient's likelihood of having heart conditions like atrial fibrillation, amyloidosis, aortic stenosis, low ejection fraction, hypertrophic cardiomyopathy (HCM) and more The AI can also predict a patient's biological age using traditional 12-lead and
  • Expert Alert: Cardiac amyloidosis masquerades as other conditions; 1 . . .
    ROCHESTER, Minn ― Human bodies constantly produce thousands of perfectly folded proteins, but some proteins get misfolded An excess of these misfolded proteins can overwhelm the body's ability to remove them When that happens, the rogue proteins bind together and form a substance called amyloid Webs of amyloid can deposit in any tissue or organ, […]
  • Mayo Clinic Minute: Know the warning signs of hypertrophic . . .
    Dr Said Alsidawi, a Mayo Clinic cardiologist, explains hypertrophic cardiomyopathy and the warning signs to be aware of
  • Women in science: Q A with Martha Grogan, M. D.
    With researchers Marina Ramirez-Alvarado, Ph D and Angela Dispenzieri, M D , Dr Grogan co-leads the Mayo Amyloid Team, a leader in amyloidosis research and treatment Dr Grogan's areas of clinical research include studies analyzing diagnostic imaging, treatment and outcomes for patients with cardiac amyloidosis
  • Mayo Clinic Q and A: Treating orthostatic hypotension
    Orthostatic hypotension can develop for many reasons It could be the result of something as simple as dehydration or as complex as a nervous system disorder Diabetes is a common cause of orthostatic hypotension Rarer causes include heart valve disorders, amyloidosis, extremely low heart rate, Addison’s disease and Lewy body dementia Some





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