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  • Isatin - an overview | ScienceDirect Topics
    Isatin on reduction with LiAlH4 in THF afforded indole but reduction of N -acylisatin, which has three carbonyl groups in the system, is reduced to form N -alky indole by BH 3 in THF One-pot conversion of isatin to 2-oxindole has been achieved by reaction with hydrazine Bayer has prepared 2-oxiindole in two steps The first step is the reduction of isatin to 3-hydroxyindolin-2-one by sodium
  • A comprehensive review and recent advances on isatin . . . - ScienceDirect
    A comprehensive review and recent advances on isatin-based compounds as a versatile framework for anticancer therapeutics (2020–2025)
  • Isatin - an overview | ScienceDirect Topics
    Isatin (1) (Fig 1), 1 H- indol-2,3-dione, is a scaffold of choice in many biologically active agents Substitutions of isatin at N or phenyl ring or replacement of oxygen on C2 and C3 lead to the formation of various biologically active agents, especially antitumor drugs Some review articles illustrating the chemistry and biological activity of isatins have been published Reviews that
  • Biochemical and pharmacological characterization of isatin and its . . .
    The chemistry of isatin and its derivatives Fundamental reactivity of isatin and its derivatives The presence of several reaction centers in isatin and its derivatives render them capable of participating in a large number of reactions
  • Isatin derivatives and their anti-bacterial activities
    The isatin moiety is ubiquitous in nature, and its derivatives possess diverse pharmacological properties As “privileged building blocks”, almost all positions of isatin moiety can be modified The broad spectrum of biological activities combined with a wide range of structural modifications have inspired more researchers to study isatins and create a large number of structurally diverse
  • Isatin containing heterocycles for different biological activities . . .
    Isatin derivatives occur in a variety of dyes, agricultural chemicals and pharmaceuticals, particularly in biologically active molecules Because of its unique size and privileged electronic properties, in these years, there is considerable interest in the development and pharmacology of isatin derivatives for their diverse activities
  • Design of high-performance branched Poly (aryl ether isatin) anion . . .
    In summary, we have successfully designed and synthesized a novel series of poly (aryl ether isatin) anion exchange membranes (TPEP-Pip-OH-x) via a cost-effective superacid-catalyzed route that reduced reagent consumption by 30 %
  • Isatin-based microporous polymer membranes with tunable building blocks . . .
    In this study, we synthesized microporous polymer membranes using electrophilic isatin and nucleophilic aromatic building blocks via super-acid-cataly…
  • Isatin-modified Calixarene derivatives: A comprehensive study on . . .
    Calixarene-isatin derivatives were also observed to have antibacterial and antifungal activity From the evaluation of the study as a whole, it can be concluded that all test compounds were active against S lutea and that this bacterium was the most sensitive micro-organism





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